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Anesthetic Molecule Interaction of Noble Gases with Proteins and Lipids and their Effect: A Review

[ Vol. 15 , Issue. 10 ]

Author(s):

Shyamal Kumar Kundu*, Chiranjib Chakraborty, Shin Yagihara, Seong Lin Teoh and Srijit Das*   Pages 1381 - 1392 ( 12 )

Abstract:


Surgical operations are impossible without administering proper analgesia. Advancement in the field of anesthesia has invariably resulted in the accomplishment of all surgical processes without any inconvenience. Admittedly, the use of noble gas is on the decline. The noble gases may not interact chemically with any other substance under normal temperature and pressure but they may interact with proteins and lipids. Different anesthetic molecules may stimulate either proteins or lipids in membrane. There is a connection between the anesthetic molecules and the hydrophobic region of the membrane. In the present review, we attempt to highlight the interaction between the anesthetic molecule with proteins and lipids and their effects. We sketched few noble gases and some other existing molecules such as halothane and alcohol which interacted with proteins and lipids.

Keywords:

Anesthesia, interactions, protein, lipids, effect, membrane.

Affiliation:

Department of Physics, School of Basic and Applied Sciences, Galgotias University, Greater Noida 203201, Department of Bioinformatics, School of Computer Sciences, Galgotias University, Greater Noida 203201, Department of Physics, Tokai University, Hiratsuka-Shi, Kanagawa 259-1292, Department of Anatomy, Universiti Kebangsaan Malaysia Medical Centre, 56000 Kuala Lumpur, Department of Anatomy, Universiti Kebangsaan Malaysia Medical Centre, 56000 Kuala Lumpur

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