Submit Manuscript  

Article Details


Topical and Transdermal Drug Delivery: From Simple Potions to Smart Technologies

[ Vol. 16 , Issue. 5 ]

Author(s):

Heather A.E. Benson*, Jeffrey E. Grice, Yousuf Mohammed, Sarika Namjoshi and Michael S. Roberts   Pages 444 - 460 ( 17 )

Abstract:


This overview on skin delivery considers the evolution of the principles of percutaneous absorption and skin products from ancient times to today. Over the ages, it has been recognised that products may be applied to the skin for either local or systemic effects. As our understanding of the anatomy and physiology of the skin has improved, this has facilitated the development of technologies to effectively and quantitatively deliver solutes across this barrier to specific target sites in the skin and beyond. We focus on these technologies and their role in skin delivery today and in the future.

Keywords:

History, skin delivery, nanotechnology, physical enhancement, microneedles, minimally invasive, transdermal technologies, targeted delivery, stratum corneum, follicular transport, wearable devices.

Affiliation:

School of Pharmacy and Biomedical Sciences, Curtin Health Innovation Research Institute, Curtin University of Technology, Perth, Diamantina Institute, The University of Queensland, Translational Research Institute, QLD, 4102, Diamantina Institute, The University of Queensland, Translational Research Institute, QLD, 4102, Diamantina Institute, The University of Queensland, Translational Research Institute, QLD, 4102, Diamantina Institute, The University of Queensland, Translational Research Institute, QLD, 4102

Graphical Abstract:



Read Full-Text article