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Role of novel drug delivery systems in coronavirus disease-2019 (covid-19): time to act now

Author(s):

Neeraj Mittal, Varun Garg, Sanjay Kumar Bhadada and O. P. Katare*   Pages 1 - 10 ( 10 )

Abstract:


The corona virus disease 2019 (COVID-19) has found its roots from Wuhan (China). COVID-19 is caused by a novel corona virus SARS-CoV2, previously named as 2019-nCoV. COVID-19 has spread across the globe and declared as pandemic by World health organization (WHO) on 11th March, 2020. Currently, there is no standard drug or vaccine available for the treatment, so repurposing of existing drugs is the only solution. Novel drug delivery systems (NDDS) will be boon for the repurposing of drugs. The role of various NDDS in repurposing of existing drugs for treatment of various viral diseases and their relevance in COVID-19 has discussed in this paper. It focuses on the currently ongoing research in the implementation of NDDS in COVID-19. Moreover it describes the role of NDDS in vaccine development for COVID-19. This paper also emphasizes how NDDS will help to develop the improved delivery systems (dosage forms) of existing therapeutic agents and also explore the new insights to find out the void spaces for a potential targeted delivery. So in these tough times, NDDS and nanotechnology can be a safeguard to humanity.

Keywords:

Anti-viral, COVID-19, nanoparticles, novel drug delivery system, repurposing, vaccine.

Affiliation:

Department of Endocrinology, Postgraduate Institute of Medical Education & Research, Chandigarh-160012, Department of Medical Affairs, Cadila Healthcare Limited, Ahmedabad 382421, Gujarat, Department of Endocrinology, Postgraduate Institute of Medical Education & Research, Chandigarh-160012, University Institute of Pharmaceutical Sciences, UGC Centre of Advanced Studies, Panjab University, Chandigarh-160014



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